UsrClass.dat locked

UsrClass.dat and UsrClass.dat.log are both locked when I try to delete a profile. They are kept in the location

C:\Documents and Settings\%Username%\Local Settings\Application Data\Microsoft\Windows\

Suggested methods to delete this uses UPHClean.

I have installed this on the server and restarted the server as well, as this was another suggestion to break the link to the file in use.